Omicron subvariant BA2 is able to reinfect omicron recoverees

dickf3 said:

For instance: was the ancestral strain unable to reinfect someone who had recovered from Covid-19 back in early spring 2020?

That is a question I haven't looked into. I believe we would have heard about that but I don't know. I took the tone of that report as being surprised that reinfections were happening with such a similar variant.  


ml1 said:

in Monmouth County today, it turns out COVID is over.  Very few masks on people in the Ocean Twp. Wegman's.

I was in Asbury Park last Saturday when it was warm. I walked into the Convention Center and it was packed and I may have been the only one wearing a mask. It’s a big room, but it was uncomfortable to say the least.


Denmark lifted most restrictions.  They saw a sharp increases in infections but the number of new infections now seems to be declining.

There is no particular appetite for mask and vaccine mandates any more and it is politically costly for elected officials to keep pushing mandatory measures.


tjohn said:

Denmark lifted most restrictions.  They saw a sharp increases in infections but the number of new infections now seems to be declining.

There is no particular appetite for mask and vaccine mandates any more and it is politically costly for elected officials to keep pushing mandatory measures.

even if it's not mandatory, I don't get why people want to risk getting a case of COVID.  If the flu was running as rampant as Omicron, I wouldn't want to catch that either, even though it's really unlikely to have serious consequences.

what kind of person doesn't care about being flat on their back with fever and chills for a week?  It's weird that this got so political that people won't take the most easy and basic precaution to avoid getting sick.


EDITED TO ADD:  OUTDATED ARTICLE, SORRY. 

WPVI-TV: NJ COVID tracker: Sussex, Salem and Ocean counties among highest coronavirus case rates in New Jersey and country. 
https://6abc.com/covid-nj-omicron-variant-coronavirus-in-new-jersey-surge/11312982/


Jasmo said:

WPVI-TV: NJ COVID tracker: Sussex, Salem and Ocean counties among highest coronavirus case rates in New Jersey and country. 
https://6abc.com/covid-nj-omicron-variant-coronavirus-in-new-jersey-surge/11312982/

Really? I would think they woud be on the lower end.


Sorry, my citation was outdated. I still recall reading somewhere that Ocean county has very high rates currently. 

PeterWick said:

Jasmo said:

WPVI-TV: NJ COVID tracker: Sussex, Salem and Ocean counties among highest coronavirus case rates in New Jersey and country. 
https://6abc.com/covid-nj-omicron-variant-coronavirus-in-new-jersey-surge/11312982/

Really? I would think they woud be on the lower end.


ml1 said:

tjohn said:

Denmark lifted most restrictions.  They saw a sharp increases in infections but the number of new infections now seems to be declining.

There is no particular appetite for mask and vaccine mandates any more and it is politically costly for elected officials to keep pushing mandatory measures.

even if it's not mandatory, I don't get why people want to risk getting a case of COVID.  If the flu was running as rampant as Omicron, I wouldn't want to catch that either, even though it's really unlikely to have serious consequences.

what kind of person doesn't care about being flat on their back with fever and chills for a week?  It's weird that this got so political that people won't take the most easy and basic precaution to avoid getting sick.

I don't claim to understand the thought process.  And I think it is just plain rude and inconsiderate to go into a place that all people need to enter like a supermarket without a mask.  But it is what it is and it seems like a fight not worth fighting at this point.


Jasmo said:

Sorry, my citation was outdated. I still recall reading somewhere that Ocean county has very high rates currently. 

PeterWick said:

Jasmo said:

WPVI-TV: NJ COVID tracker: Sussex, Salem and Ocean counties among highest coronavirus case rates in New Jersey and country. 
https://6abc.com/covid-nj-omicron-variant-coronavirus-in-new-jersey-surge/11312982/

Really? I would think they woud be on the lower end.

At some point in December, Essex County was the #1 county in the United States for new case rate per 100,000 people. Now we are back to pre-Omicron numbers, about 125 new cases per day.  During peak Omicron in early January, we were at over 4,000 new cases per day. What a difference six weeks can make.


https://twitter.com/DrEricDing/status/1494746690787717124?s=20&t=hfn2VXF-vM3qoD9Z_IepIA

Eric Feigl-Ding@DrEricDing⚠️Worrisome—New lab experiments from Japan show that #BA2 may have features that make it as capable of causing serious illness as older variants–including Delta! And yet as evasive as old #Omicron cousin BA1. #BA2


The antibody drugs that have been useful against earlier COVID versions have lost their effectiveness against the omicron lineage. Unfortunately I do not have a subscription to Medscape so I can only post the first few lines.

https://www.medscape.com/viewarticle/968402

The sole COVID-19 monoclonal antibody therapy shown to be effective for patients infected with the Omicron variant - sotrovimab from Vir Biotechnology and GSK - is unlikely to do as well against at least one new version of the variant spreading globally, new research suggests.

The World Health Organization is currently monitoring several Omicron sublineages. Data posted on bioRxiv ahead of peer review showed that the rapidly spreading BA


I’m posting here because, now that ‘hysteria around omicron and restrictions is waning’, our Health Departments are somewhat alarmed to find that chickenpox not  4 kinds of flu they were anticipating - good old chickenpox is arising and looking like an old-fashioned epidemic.

https://www.abc.net.au/news/2022-02-22/varicella-defies-covid-restrictions/100850390


joanne said:

I’m posting here because, now that ‘hysteria around omicron and restrictions is waning’, our Health Departments are somewhat alarmed to find that chickenpox not  4 kinds of flu they were anticipating - good old chickenpox is arising and looking like an old-fashioned epidemic.

https://www.abc.net.au/news/2022-02-22/varicella-defies-covid-restrictions/100850390

Makes me glad I got my first shingles jab earlier this month. I caught chickenpox from a GF in college who had shingles and was ridiculous pain with it, so I stayed with her the entire time. It was a bank holiday weekend, the college doctor's office was closed, we didn't know what it was and eventually we went to the ER and got it diagnosed, but by that time I was already infected. Quarantined at my sister's house (away on vacation) for 2 weeks. Both diseases suck. Edit: Get the vaxx if you can!


ridski said:

joanne said:

I’m posting here because, now that ‘hysteria around omicron and restrictions is waning’, our Health Departments are somewhat alarmed to find that chickenpox not  4 kinds of flu they were anticipating - good old chickenpox is arising and looking like an old-fashioned epidemic.

https://www.abc.net.au/news/2022-02-22/varicella-defies-covid-restrictions/100850390

Makes me glad I got my first shingles jab earlier this month. I caught chickenpox from a GF in college who had shingles and was ridiculous pain with it, so I stayed with her the entire time. It was a bank holiday weekend, the college doctor's office was closed, we didn't know what it was and eventually we went to the ER and got it diagnosed, but by that time I was already infected. Quarantined at my sister's house (away on vacation) for 2 weeks. Both diseases suck. Edit: Get the vaxx if you can!

Agree with ridski.

Get vaxxed for Shingles.  You do not want to get it.


yahooyahoo said:

ridski said:

joanne said:

I’m posting here because, now that ‘hysteria around omicron and restrictions is waning’, our Health Departments are somewhat alarmed to find that chickenpox not  4 kinds of flu they were anticipating - good old chickenpox is arising and looking like an old-fashioned epidemic.

https://www.abc.net.au/news/2022-02-22/varicella-defies-covid-restrictions/100850390

Makes me glad I got my first shingles jab earlier this month. I caught chickenpox from a GF in college who had shingles and was ridiculous pain with it, so I stayed with her the entire time. It was a bank holiday weekend, the college doctor's office was closed, we didn't know what it was and eventually we went to the ER and got it diagnosed, but by that time I was already infected. Quarantined at my sister's house (away on vacation) for 2 weeks. Both diseases suck. Edit: Get the vaxx if you can!

Agree with ridski.

Get vaxxed for Shingles.  You do not want to get it.

the pandemic reminded me of other vaccines I needed.  Got both Shingrix shots at the end of last year.  Actually had a similar reaction to each that I had to the 2nd COVID shot -- half a day of chills and body aches, and some fatigue.  But a LOT better than a case of shingles.


I recall reading recently (not sure where or I would linc it), that the Moderna and Pfizer covid vaccines, three shots series, do indeed provide a long-lasting at least partial immunity to covid.   This would be a year or more immunity and it is incorporated into parts of the immune system that we do not usually see in the usual measurements.   Did I really read this, or was I over-optimistically imagining it in what I read?


I suppose the date of that report would put it in better context. Much of the commentary on the effectiveness of COVID vaccines had to be reconsidered once the omicron variant emerged. It is so different from earlier COVID virus versions. Duo you recall where you read it?


I do not recall where I read it, but it was a couple of weeks ago, I could not find it with a Google search.  The gist of the story, as I recall, is that the covid vaccine has a long-lasting antibody recall in parts of the immune system and not just in the T cells as is most often reported.   My sense was that the immune system has many cellular parts and that some of these cell parts do indeed have a covid memory.  I am sorry that I do not have better info.  


RobertRoe said:

I do not recall where I read it, but it was a couple of weeks ago, I could not find it with a Google search.  The gist of the story, as I recall, is that the covid vaccine has a long-lasting antibody recall in parts of the immune system and not just in the T cells as is most often reported.   My sense was that the immune system has many cellular parts and that some of these cell parts do indeed have a covid memory.  I am sorry that I do not have better info.  

it was in an obscure journal called the NYT yesterday grin

https://www.nytimes.com/2022/02/21/health/covid-vaccine-antibodies-t-cells.html


It may have been an article like this:   https://www.science.org/doi/10.1126/sciimmunol.abl9105

This article was pre-omicron.  


ml1 said:

the pandemic reminded me of other vaccines I needed.  Got both Shingrix shots at the end of last year.  Actually had a similar reaction to each that I had to the 2nd COVID shot -- half a day of chills and body aches, and some fatigue.  But a LOT better than a case of shingles.

My Shingrix reaction was far worse (exactly as you described) than my COVID shot reaction, but then I didn't have any reaction to my COVID shots at all. 


Denmark has not been a fount of good news lately. Not only has BA.2 been more transmissible it is also developing more mutations with a bite of their own.

Possible new mutation in BA.2 growing as proportion of all BA.2 in Denmark. ORF1a:M85del (NSP1:M85del) around 10% of sequences in Denmark.

https://twitter.com/DrEricDing/status/1496238419806203910


ml1 said:

it was in an obscure journal called the NYT yesterday
grin

https://www.nytimes.com/2022/02/21/health/covid-vaccine-antibodies-t-cells.html

The article discusses the results of a study that collected data from June to December of 2021.

Review of Pre-Omicron Data Finds COVID-19 Vaccine Protection From Severe Disease Remains Strong at Six Months

https://publichealth.jhu.edu/2022/review-of-pre-omicron-data-finds-covid-19-vaccine-protection-from-severe-disease-remains-strong-at-six-months

Study reviewed dozens of evaluations of four vaccines—Pfizer, Moderna, Janssen, AstraZeneca— published last year from June 17 to December 2

An analysis of research literature published last year before the omicron variant took hold found that while COVID-19 vaccines lose some effectiveness in preventing SARS-CoV-2 infection, the vaccines retain nearly all of their ability to prevent severe disease up to six months after full vaccination. The study, which appears online February 21 in The Lancet, was led by researchers at the Johns Hopkins Bloomberg School of Public Health and the World Health Organization.

For their study, the researchers analyzed vaccination effectiveness data published last year from June 17 to December 2 in both peer-reviewed journals and on preprint servers, which post papers ahead of peer review. The data—detailed in 24 papers—covered dozens of individual vaccine evaluations preceding the emergence of the currently dominant omicron variant.

----------------------------

From the news article about the study's results:

Key points from the study:

  • In the six months following full vaccination, the level of protection from COVID-19 infection fell by about 21 percentage points.
  • BUT—the level of protection against severe disease fell by only about ten percentage points in the same interval.
  • This means that a vaccine providing 90 percent protection from infection at one month would provide 69 percent protection at six months.
  • Protection against symptomatic illness dropped around 24.9 percentage points among persons of all ages.
  • Protection against symptomatic illness dropped about 32 percentage points among older persons, from one month to six months post-vaccination.
  • The study suggests that, pre-omicron, the four vaccines have provided good protection against severe outcomes.

The Y-axis on the new daily deaths graph has numbers that are thankfully so much lower than the U.S.'s numbers. However, when you compare the Y-axis on the new daily cases graph with ours, the amounts are much closer. Denmark saw a phenomenal increase in the daily case count compared with any period of theirs in this pandemic. That is a mutational nightmare.


My Community Services teacher was telling us this morning that her second shot of whichever vax, provoked a heart attack several hours later. (I suspect she had a Moderna). As a former nurse who had carefully done her research because she’d had a heart attack some months prior to the first shot, she’s furious and now feels we’ve been forced into unsafe choices that aren’t true choices at all. 
It’s really left her in a bad way.


joanne said:

My Community Services teacher was telling us this morning that her second shot of whichever vax, provoked a heart attack several hours later. (I suspect she had a Moderna). As a former nurse who had carefully done her research because she’d had a heart attack some months prior to the first shot, she’s furious and now feels we’ve been forced into unsafe choices that aren’t true choices at all. 
It’s really left her in a bad way.

quite, quite unlikely that the vaccine caused her heart attack. (hell, she just had a heart attack recently)

and what research? of what, exactly?

things always occur after other things occur. a single event is hardly a way to define causality.


Her cardiac specialist confirmed she’s one of the very small number to have had the cardiac reaction.  (She feels there aren’t enough warnings, readily available, for people who shouldn’t be taking these meds. Instead, too much effort went into reassuring people how safe they were.) 

The really silly thing here in Australia is that each person is left to do their own research then consult with the family doc or a specialist, instead of first being advised appropriately by a knowledgeable doc familiar with your case history. Weird. Counter to nearly every other vaccination program we run.


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